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โ† Trials
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Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota

RecruitingNAAges 18 Years - 45 YearsAllPurdue University
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In plain words

What the trial is, and whether it could suit you

The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin. Along with investigating the impact of native chicory on bowl habits, mood and appetite. The two main questions this study aims to answer: * To what extent do differences exist in rate of change over time between individuals in gut microbiota response (Bifidobacterium growth) to native chicory inulin supplementation. * To what extent do differences exist between individuals in persistence of the gut microbiota upon stopping supplementation. The effects of native chicory inulin on gut microbiota response will be compared to a maltodextrin placebo to sure changes in gut microbiota result directly from chicory inulin supplementation. Participants will firstly complete a one-week run-in phase to establish

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * adults aged 18-45 * BMI \>18.5 - \< 30 kg/m2 * Regular bowel movements (\> 4 days per week) Exclusion Criteria: * Self-reported sensitivity to FODMAPs and following a low FODMAP diet ((FODMAPS stands for fermentable oligosaccharides, disaccharides, monosaccharides and polyols). * Self-reported food allergies and sensitivities including gluten, dairy, nuts, soya and lactose etc. * Self-reported antibiotic treatment in the past 6 months. * Self-reported history of gastrointestinal disease and/or heart disease, cardiovascular, liver, and respiratory disorders, cancer and/or clinically relevant (pre) diabetes. * Self-reported to having undergone major surgery of the gastrointestinal tract, with the exception of cholecystectomy and appendectomy. * Self-reported smoking and/or self-reported drug or alcohol abuse. * Self-reported history of psychiatric and/or mood disorders including eating disorders. * Self-reported to be following a restrictive diet (i.e. ketogenic, intermittent fasting). * Pregnant and lactating women.
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What it tests

  • Inulin
  • Maltodextrin
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Where

1 site
Purdue University
West Lafayette, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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