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The Effect of the Type of Conduit-duct Anastomosis Technique on the Postoperative Course in Patients Undergoing Liver Transplantation

RecruitingNAAges 18 Years - 75 YearsAllMedical University of Warsaw
NCT06533592 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The main objective of the trial is to compare the effect of two end-to-end duct-to-duct anastomosis surgical techniques using the continuous suture method versus interrupted method (control group) on reducing the risk of bile leakages in the 90-day follow-up period after liver transplantation and other postoperative complications resulting from them i.e.: the occurrence of a critical stenosis in the duct-to-duct anastomosis within 90 days. In addition, as part of the research experiment, long-term biliary complications will be assessed, i.e. occurring over a period of more than 90 days (a 2-year observation period of patients was assumed). As part of the trial 284 patients qualified for the procedure of liver transplantation from a deceased donor will be included, in whom end-to-end anastomosis of the bile ducts will be performed. After entering the study, patients will be randomized to

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📋 Eligibility rules (as published)
Inclusion Criteria: * age over 18 * elective liver transplantation * informed consent to participate in the study * recipient bile duct diameter over 3mm * donor bile duct diameter over 3mm Exclusion Criteria: * age below 18 * pregnancy * living donor liver transplantation * split-liver or reduced-size liver transplantation * liver transplantation other than from brain death donor * liver transplantation with hepaticojejunostomy * patients undergoing re-transplantation * multi-organ transplantation * recipient bile duct diameter below 3mm * donor bile duct diameter below 3mm
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What it tests

  • Continous suture technique
  • Interrupted suture technique
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Where

1 site
Department of General, Transplantation and Liver Surgery UCC MUW
Warsaw, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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