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Long-term Follow-up of Children Born in the PETN Studies

Recruitingn/aAges 6 Years - 18 YearsAllJena University Hospital
NCT06534307 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In every 10th pregnancy, the child in the uterus is insufficiently nourished, a so-called growth retardation. This occurs when the child cannot reach its growth potential due to an undersupply in the uterus. This inadequate supply is considered a developmental cause for the later development of physical diseases like cardiovascular diseases, sugar metabolism disorders and obesity as well as mental developmental problems (for example problems in cognitive skills, deficits in language development, concentration and attention). From 2002 to 2008, 111 patients with impaired placental blood flow were included in a small study and treated with Pentalong or placebo. From 2017 to 2022, the positive effects of the study treatment were tested on a larger number of patients. A total of 317 pregnant women were included at 14 participating study centers in Germany. In this follow-up study, the deve

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📋 Eligibility rules (as published)
Inclusion Criteria: * mothers participation in one of the PETN studies * age above 5 years * completion of questionnaires for self reported data * written consent for physical examination Exclusion Criteria - only physical examination: * physical and mental states preventing physical examination
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What it tests

  • Questionnaire Child Behaviour Checklist
  • Questionnaire Young Self Report
  • physical examination
  • metabolic examination
  • Questionnaire Reynolds Intellectual Assessment Scales and Screening
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Where

13 sites
Universitäts-Frauenklinik Tübingen
Tübingen, Germany
Universitätsklinikum Ulm
Ulm, Germany
Klinikum der Universität München
München, Germany
Städtisches Klinikum München
München, Germany
Medizinische Hochschule Hannover
Hanover, Germany
Universitätsklinikum Bonn
Bonn, Germany
Universitätsklinikum Dresden
Dresden, Germany
Uniklinikum Leipzig
Leipzig, Germany

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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