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Interest of Late Images for the Assessment of Extensions in 18FGD PET-CT of Muscle-Invasive Bladder Cancers

RecruitingNAAges 18 Years - anyAllHopital Foch
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to demonstrate a significant gain in sensitivity versus surgical curage (extended pelvic) for initial lymph node staging of late FDG-PET images (2.5 hours) versus standard images (1 hour), analyzed by side (right iliac/left iliac areas in Patients with muscle-invasive bladder tumor (MIBT) (≥pT2) referred for FDG-PET in the nuclear medicine department of Hôpital Foch as part of their initial extension workup. Before performing 18FDG PET-CT, the operator checks that the patient has fasted for at least 6 hours and that blood glucose levels are below 11 mmol/l. In the absence of contraindication, intravenous (IV) injection of the radiopharmaceutical (18FDG at a dose of 3 MBq/kg) and a diuretic (Furosemide 20mg) will be performed as part of routine care. The 18FDG PET-CT scan will be performed in 2 phases: 1st phase: Standard acquisition (vertex to mid-thigh) at 1

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient 18 years of age or older, * With histologically proven muscle-invasive bladder cancer (≥pT2) at endoscopic bladder resection, * Scheduled to undergo 18FDG PET-CT in the nuclear medicine department at Hôpital Foch, * Having signed a consent form, * Affiliated to a health insurance scheme. Exclusion Criteria: * Patient with a history of pelvic or genitourinary cancer, * Patient with known metastatic disease, * Patient with a contraindication to 18FDG PET-CT, * Pregnant or breast-feeding woman, * Patient deprived of liberty or under guardianship.
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What it tests

  • 18FDG PET-CT
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Where

1 site
Hopital Foch
Suresnes, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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