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Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery

Recruitingn/aAges 18 Years - anyAllUniversity of Zurich
NCT06538948 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity. Yet, the exact mechanisms governing its effect are somewhat elusive, with current research mainly focusing on post-operative food intake outcomes based on self-reported data, which might not fully capture the nuanced changes in eating behaviours. To address these gaps, our study plans to employ the newly developed "drinkometer", a device capable of analysing the intricate changes in drinking behaviour following BS. This tool promises to bring a more detailed perspective to the changes in ingestive behaviours, bypassing the inaccuracies of self-reporting methods. By expanding our research to encompass diverse patient demographics and examining potential links to physiological shifts like gut hormone level alterations, the study aims

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 year * BMI ≥ 35 kg/m2 for patients with planned RYGB or SG operation * BMI ≥ 30 kg/m2 for external controls affected by obesity but no planned RYGB or SG within the next 12 months, and * BMI ≥ 18.5 kg/m2 and ≤ 24.9 kg/m2 for controls without obesity. Exclusion Criteria: * history of previous bariatric operations and/ or revisional surgery (e.g., alteration of limb lengths after primary RYGB), * smoking, * established diagnosis of type 1 or 2 diabetes mellitus, and * polycystic ovary syndrome (PCOS).
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What it tests

  • Bariatric Surgery
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Where

2 sites
Hospital Männedorf
Männedorf, Switzerland
University Hospital Zurich, Department of Surgery and Transplantation
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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