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Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis

Recruitingn/aAges 18 Years - anyAllFederal Research and Clinical Centre of Intensive…
NCT06545786 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients. These disorders can affect cognitive functions for years, deteriorating quality of life and increasing hospital stays and medical costs. Diagnosing PND is challenging due to their varied manifestations, such as memory and attention problems, and the lack of standardized criteria and biomarkers. One well-studied form of PND is postoperative delirium (POD). According to the ICD-10, POD is an organic cerebral syndrome characterized by disturbances in consciousness, attention, perception, and other cognitive functions. Researchers suggest that POD development involves a combination of predisposing and precipitating factors. Electroencephalography (EEG) has been used in anesthesiology to assess anesthesia depth and intraoperative awareness. Modern EEG analysis met

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Scheduled non-cardiac surgery of intermediate or high risk * General anesthesia using inhalational anesthetics * Informed consent from the patient to participate in the study Exclusion Criteria: * Preoperative MMSE score less than 20 points * History of any mental illness * Use of psychotropic drugs within 1 month prior to inclusion in the study * Presence of neuromuscular diseases * Neurosurgical procedures * Inability to undergo preoperative testing for any reason
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What it tests

  • Intraoperative electroencephalography
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Where

1 site
City clinical hospital named after SS Yudin
Moscow, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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