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Drug Response Profiling (DRP) Registry Zurich for Hematological Malignancies

Recruitingn/aAges any - 40 YearsAllUniversity Children's Hospital, Zurich
NCT06550102 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a prospective, non-randomized feasibility study of drug response profiling (DRP) in pediatric blood cancers. Primary cancer cells are isolated from patients and screened ex vivo at single-cell resolution using automated fluorescence microscopy. Drug sensitivity fingerprints are integrated with genetic annotations to inform the treating physician about personalized treatment options. The study aims to determine the practicability of real-time drug response profiling and its actionability in identifying patient-specific cancer dependencies in refractory disease settings.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pediatric and adult patients below the age of 40 years * Diagnosis of hematological malignancy (primary, relapsed or refractory) including leukemia, myeloma or lymphoma * Tumor material collected as part of routine diagnostics and willingness to donate tumor material for translational research * Patient and/or guardian has signed the informed consent of the DRP registry or of a clinical trial which includes DRP as add-on research. Exclusion Criteria: * Missing informed consent for the registry or of a clinical trial which includes DRP as add-on research
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What it tests

  • Not listed
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Where

1 site
University Children's Hospital Zurich
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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