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Vitamin D Replacement in Bronchiectasis

RecruitingPhase 4Ages 18 Years - anyAllQueen Mary Hospital, Hong Kong
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In plain words

What the trial is, and whether it could suit you

This study seeks to address the limitations in previous related studies on vitamin D replacement and bronchiectasis exacerbation occurrence through a self-controlled pilot study. The investigators aim to investigate whether vitamin D replacement in bronchiectasis patients with vitamin D deficiency can reduce hospitalized bronchiectasis exacerbation occurrence. Patients who participated in the prior study entitled "Prospective clinical study on serum 25-hydroxyvitamin D (25-OH D) level and risk of bronchiectasis exacerbation" (UW 22-317) will be invited for participation during regular clinic follow-up and management in Queen Mary Hospital. If participants are willing to join the further research, participants will be recruited in this self-controlled study. There are some differences from usual management to non-CF bronchiectasis subjects. The study subjects would be checked for their bl

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. ages 18 years or above, male or female. 2. confirmed diagnosis of non-CF bronchiectasis based on high-resolution computed tomography (HRCT) scan. 3. participation in the prior study entitled "Prospective clinical study on serum 25-hydroxyvitamin D (25-OH D) level and risk of bronchiectasis exacerbation" (UW 22-317) Exclusion Criteria: 1. underlying asthma, COPD and other co-existing respiratory diseases 2. underlying osteoporosis 3. supplementary Vitamin D in their regimen 4. advanced chronic kidney disease with estimated glomerular filtration rate (eGFR) \< 30mL/min
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What it tests

  • Vitamin D3
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Where

1 site
Queen Mary Hospital
Hong Kong, Hong Kong
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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