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Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison

Recruitingn/aAges 18 Years - 75 YearsAllLoma Linda University
NCT06553131 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response. The response to, and recovery from, medications that relax the muscles are best described for a nerve in the arm called the ulnar nerve. The investigators believe that other nerves in the arm, such as the median nerve, could be used to monitor the amount of muscle relaxation. The purpose of this study is to compare the muscle response at two different nerve sites after giving medications to relax the muscles. This study is going to measure the depth of muscle relaxation during surgery at two different sites. The muscle response to stimulation of the ulnar nerve (located in the arm) will be compared to the muscle response to stimulation of the median nerve (also located in the arm).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults 18 - 75 years of age who are able to provide consent * Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours Exclusion Criteria: * Contraindication to rocuronium use * Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and/or pharmacokinetics, such as: * Neuromuscular disease * Expected or known difficult airway * Rocuronium allergy * BMI \< 18.5 or \> 40 * History of adhesive allergy * Upper extremity weakness, limb deformity, or absence of all or part of an upper limb * Patients undergoing surgical procedures requiring cardiopulmonary bypass
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What it tests

  • Neuromuscular Transmission Monitoring
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Where

1 site
Loma Linda University Troesch Medical Center
Loma Linda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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