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โ† Trials
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Safety and Efficacy of the CoolCryo System for Cardiac Cryoablation in the Treatment of Atrial Fibrillation

Recruitingn/aAges 18 Years - anyAllMedinice S.A.
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In plain words

What the trial is, and whether it could suit you

The study involves endocardial cryoablation of the left and/or right atrium of the heart using the CoolCryo system as an adjunct to mitral valve surgery, with the aim of eliminating atrial fibrillation (AF), which is a common sequelae of mitral valve defects and is associated with an increased risk of ischaemic stroke, heart failure and death.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Written consent from the patient to participate in the study. 2. age โ‰ฅ18 years. 3. patient qualified for mitral valve surgery (mitral valve plication or mitral valve replacement "with" or "without" left atrial appendage closure). 4. a documented diagnosis of co-occurrence of paroxysmal or persistent atrial fibrillation (AF) since at least 3 months prior to surgery with exclusion of acute conditions. Exclusion Criteria: 1. Lack of written consent from the patient to participate in the study. 2. Failure to meet the inclusion criteria. 3. Contraindications to the cryoablation procedure. 4. Patient breastfeeding, pregnant or planning pregnancy within 6 months of study treatment. 5. co-morbidities and/or conditions that may cause atrial fibrillation (uncompensated hyperthyroidism or hypothyroidism, acute infection, pheochromocytoma, significant dyselectrolitemia). 6. significant calcification of the left atrium. 7. Condition after previous cardiac surgery. 8. significant left atrial enlargement (size greater than 10 cm on echocardiography in one of the projections performed). projection). 9. the patient is currently a participant in another clinical trial. 10. The patient is on active biological therapy. 11. emergency surgery. 12. Life expectancy \<12 months. 13. Any circumstances that, in the opinion of the Investigator, may prevent the patient from participating in the study, limit the ability to perform the procedures outlined in the study protocol or place an unreasonable risk on the patient.
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What it tests

  • Not listed
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Where

2 sites
Antoni Jurasz University Hospital No. 1
Bydgoszcz, Poland
Silesian Centre for Heart Diseases
Zabrze, Poland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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