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โ† Trials
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Determine the Frequency of Variants in the GBA/PSAP Genes in Patients With MM or MGUS

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Rouen
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In plain words

What the trial is, and whether it could suit you

No effective specific treatment is currently available for the management of Multiple Myeloma (MM) and Monoclonal Gammopathy of Undetermined Significance (MGUS). A better understanding of the pathophysiological mechanisms would make it possible to propose treatments specifically targeting the deregulated pathways.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Major patients with multiple myeloma (MM) (defined by clonal proliferation of tumour plasma cells (\>10%), presence of a monoclonal peak in serum or urine (excluding non-secretory myeloma) and organ involvement secondary to bone marrow invasion) or with MGUS (defined as bone marrow plasmacytosis of less than 10%, associated with a monoclonal protein of less than 30g/L and no clinical involvement). * Membership of a social security scheme * Adult having read and understood the information letter and signed the consent form Exclusion Criteria: * Person deprived of liberty by an administrative or judicial decision or person placed under court protection / sub-guardianship or guardianship
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What it tests

  • Evaluation of the presence and number of mutated alleles of the GBA/PSAP genes in patients with MM or MGUS
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Where

2 sites
Centre Henri Becquerel
Rouen, France
University Rouen Hospital
Rouen, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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