🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Incidence, Characteristics and Evolution of Cerebral Vasospasm With Clinical Impact in Moderate to Severe Traumatic Brain Injury Complicated by Subarachnoid Hemorrhage at Martinique University Hospital

RecruitingNAAges 18 Years - anyAllUniversity Hospital Center of Martinique
NCT06560372 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Context : Moderate to severe head trauma with altered state of consciousness is an extremely common pathology (between 60 and 120 cases per 100 000 people per year depending on the country and age group), and is responsible for 30% of deaths by trauma. It is complicated in 30-60% of cases by subarachnoid hemorrhage (SAH), which makes it the leading cause of SAH. SAH and its complications are well described when the origin is aneurysmal, notably cerebral vasospasm (CV) because it promotes delayed cerebral ischemia with a major prognostic impact. This is why the screening and prevention of this vasospasm are well established in the literature and in practice, in the nosological context of aneurysmal SAH. Research problem : However, when it comes to post-traumatic SAH, CV is a more maligned entity, with a much less detailed description. However, when we know the prognostic interest that

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patient aged 18 or over, * Hospitalized at the Martinique University Hospital for the treatment or monitoring of a moderate or severe TBI (Glasgow Score less than or equal to 13 at initial treatment) presenting with SAH on the cerebral CT scan, * Patient if capable, or representative of the patient in case of incapacity, having been informed of the research, and having given free, informed and written consent, * After an emergency inclusion procedure if the patient's representative is initially unreachable and written agreement, informed within the first 48 hours of inclusion by the representative or the patient if his neurological condition allows it, * Be affiliated to a social security system. Exclusion Criteria: * Pregnant woman, * Presence of an aneurysmal pathology known or diagnosed at initial treatment, * History of chronic kidney failure stage 4 (creatinine clearance measured less than 30ml/min), * Imminent death of the patient, * Patient presenting criteria for non-admission to critical care (death expected within 48 hours, progressive fatal pathology with vital prognosis in less than 30 days, patient in palliative situation), * Known allergy to iodized contrast products, * Be placed under legal protection, guardianship or curatorship, * Patient or representative who refused to allow the patient to participate in the study. Additional Exclusion Criteria after patient's inclusion: * Death of the patient expected within the first 48 hours, * Minor, * Release from hospitalization against medical advice, * Transfer to another establishment before the 13th day of treatment (outside the Martinique University Hospital), * Change of opinion of the patient's representative (after neurological recovery) regarding the patient's participation in research, * Withdrawal of consent to participate in the study being supported with refusal to use the data collected until withdrawal of participation,
💊

What it tests

  • Additional realization of a brain perfusion scan sequence which would allow the radiological diagnosis of CV
📍

Where

1 site
University Hospital Center of Martinique
Fort-de-France, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy