AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surgery?

RecruitingNAAges 18 Years - anyAllClinique Pasteur Lanroze
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

Venous thrombosis and pulmonary embolism are considered serious and potentially preventable complications of hip and knee replacement surgery. The risks of thrombosis must be weighed against the risks associated with preventive measures, both mechanical and pharmacological. Modern medicine is now questioning the use of elastic restraints in surgery. Several studies have investigated the benefits of using restraints to prevent thromboembolic events. These studies have shown no additional benefit from the use of compression stockings in thromboembolism prevention. To the best of our knowledge, no orthopedic study has investigated the non-inferiority of pharmacological treatment compared with elastic compression devices, specifically in knee and hip surgery. The aim of this multicenter, prospective, randomized study is to investigate whether pharmacological prophylaxis alone is non-inferior

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * first line and non-traumatic total hip or knee arthroplasty * Patient included in an Enhanced Rehabilitation after Surgery (ERS) or "fast-track" protocol, or scheduled as an outpatient. Exclusion Criteria: * Patient requiring long-term anticoagulation for pre-existing co-morbidity * Patients with coagulation disorders (hypercoagulability) * Patient undergoing thrombogenic pharmacological treatment * History of obliterative arteriopathy of the lower limbs * Arterial disease * Obesity * Heart failure * Chronic bronchopneumopathy * Lymphedema * Chronic inflammatory disease * Permanent wearing of elastic restraints * Proximal or distal arterial bypass surgery * Creatinine clearance \< 15 ml/min * Inability to give consent * Revision surgery for hip or knee prosthesis * Metastatic cancer * Life expectancy less than 3 months * Allergy to socks or compression stockings * Patients presenting one or more exclusion criteria for the fast-track protocol (severe or poorly-balanced associated conditions such as diabetes or immunodepression, inability to contact the doctor or hospital department if necessary, pre-operative ASA score greater than or equal to 4). * Adults under guardianship or curatorship * Vulnerable persons in accordance with article L1121-6 of the CSP (French Public Health Code)
๐Ÿ’Š

What it tests

  • Pharmacological thromboprophylaxis and elastic compression
  • Pharmacological thromboprophylaxis without elastic compression
๐Ÿ“

Where

1 site
Clinique Pasteur Lanroze
Brest, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy