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Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)

RecruitingPhase 4Ages 18 Years - 60 YearsAllHuazhong University of Science and Technology
NCT06565910 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to study the analgesic effect of liposomal bupivacaine plus bupivacaine for Pericapsular Nerve Group (PENG) block in postoperative pain management following hip replacement surgery. It will also assess the safety of liposomal bupivacaine for this purpose. The main questions it aims to answer are: 1. Is liposomal bupivacaine plus bupivacaine superior to ropivacaine in terms of analgesic efficacy, duration of pain relief, opioid consumption, and patient satisfaction? 2. What medical problems do participants encounter when using liposomal bupivacaine plus bupivacaine for PENG block in postoperative pain management following hip replacement surgery? Researchers will compare liposomal bupivacaine plus bupivacaine to ropivacaine (a routinely used regional anesthetic in clinical practice) to determine if liposomal bupivacaine plus bupivacaine is more effecti

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📋 Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists(ASA) I\~II * Normal coagulation * Clinical diagnosis of hip fracture Exclusion Criteria: * Presence of severe systemic diseases or ASA grade III or higher * Allergy to amide local anesthetics
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What it tests

  • Liposomal bupivacaine plus bupivacaine
  • Ropivacaine
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Where

1 site
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, HUST
Wuhan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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