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Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction

Recruitingn/aAges 18 Years - anyAllRegion Stockholm
NCT06566625 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions (STEMI and NSTEMI, respectively) using ECG. While patients with STEMI are urgently referred to a cath lab, patients with NSTEMI usually undergo a planned invasive coronary angiography (ICA) anywhere from 24-72 hours after arriving to the hospital. When an invasive coronary angiography can not explain the cause of a myocardial infarction, an MRI of the heart (a CMR) is often done as a follow-up investigation. A growing body of evidence suggests that performing a CMR before the planned ICA can provide an accurate diagnosis and defer the need for an ICA in many of these patients with NSTEMI.

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥18 years of age Suspected NSTEMI (signs and symptoms suggest of ACS with initial ECG showing no ST-elevation) * Planned ICA where CMR can be performed without delaying ICA * Able to provide written informed consent Exclusion Criteria: * Contraindications for CMR examination with gadolinium contrast (claustrophobia, eGFR \<30ml/min/1.73m2, contrast allergy, and non-MRI compatible implants) * Arrythmias which hinder CMR examination * Previous CABG * Hemodynamic instability * Myocardial infarction \<6 months prior to inclusion
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What it tests

  • Cardiac MRI (CMR) examination
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Where

1 site
Karolinska University Hospital
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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