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Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

RecruitingNAAges 18 Years - 95 YearsAllAbhishek Parolia
NCT06569329 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to understand the effect that 3 different types of root canal procedures have on bacteria.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of pulp necrosis with apical periodontitis (AP) confirmed by pulp tests, clinical and radiographic evidence. * Tooth with no response to cold and electric pulp testing (done at screening). * Single canalled premolars with intact pulp chamber walls. * Patient must be 18 years of age or older Exclusion Criteria: * Teeth with vital pulp. * Teeth with incomplete root formation (immature with apical periodontitis). * Teeth with extensive crown destruction. * Teeth with previous endodontic treatment or intervention (pulp debridement). * Teeth with acute/ chronic apical abscess. * Teeth with internal or external resorption. * Teeth with non-odontogenic facial pain. * Teeth with periodontal pockets deeper than 4 mm. * Teeth with advanced untreated periodontal disease or recent periodontal surgery. * Teeth with mobility score greater than 2. * Teeth with a fracture or visible crack. * Patients with diabetes or immune compromised conditions. * Patients who received systemic antibiotics within the last 3 months. * Patients taking corticosteroids. * Patients who are pregnant.
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What it tests

  • GentleWave System Root Canal Therapy
  • EdgePro Laser Root Canal Therapy
  • The ProUltra Piezo Ultrasonic with EndoUltra Tips Root Canal Therapy
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Where

1 site
University of Iowa College of Dentistry and Dental Clinics
Iowa City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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