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The EEG Study Under Sevoflurane Anesthesia in Children

Recruitingn/aAges 1 Day - 6 YearsAllSecond Affiliated Hospital of Wenzhou Medical Uniโ€ฆ
NCT06580028 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Sevoflurane is one of the most commonly used volatile anesthetics in children because of its rapid induction, recovery and recovery properties. Clinical studies using noninvasive brain monitoring have shown that general anesthetics and hypnotics generate electroencephalogram (EEG) oscillations in specific spatial tissues that are fundamentally related to the structure and function of neural circuits. Slow-wave-delta (0.1-4 Hz) oscillations were present in children of all ages, and the advantage of frontal ฮฑ-wave oscillations appeared at approximately 6 months, began to be consistent at 10 months, and persisted at older ages. Another study, which analyzed EEG under sevoflurane general anesthesia in children aged 0-6 months, found that Theta and alpha wave power decreased with a decrease in sevoflurane concentrations in infants between 4 and 6 months of recovery. However, these studies lac

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. aged 1 days#6 years#; 2. with American Society of Anesthesiologists (ASA) physical status I or II#; 3. children requiring general anesthesia under sevoflurane; 4. parents or legal guardians of children who volunteered to participate in the trial; And signed the informed consent form. Exclusion Criteria: 1. Congenital malformation or other genetic conditions that are thought to affect brain development ; 2. History of severe heart, brain, liver, kidney and metabolic diseases ; 3. Premature infants (โ‰ค32 weeks); 4. Upper respiratory tract infection in the last two weeks.
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What it tests

  • Not listed
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Where

1 site
The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Wenzhou, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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