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Precision Medicine in Alzheimer's Disease : Integration of Resilience Metrics and Risk Factors - Validation Cohort BioCogBank-AD

RecruitingNAAges 50 Years - 90 YearsAllAssistance Publique - Hôpitaux de Paris
NCT06582199 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

BioCogBankAD aims at building a prospective clinical practice cohort of 244 patients with biologically confirmed mild cognitive impairment due to Alzheimer's Disease (AD) or mild AD in order to validate data regarding markers of resilience toward AD pathophysiological process discovered in an upstream project called AD-Resilience.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of AD according to IWG-2 2014 criteria * Age 50-90 year old * Affiliated or beneficiary of a social security scheme * MMSE ≥ 20 * Abnormal CSF Aβ42 or Aβ40/Aβ42 ratio according to local cut-offs * Abnormal CSF phosphorylated and total Tau according to local cut-offs * Ability to pass neuropsychological assessments * Availability of a brain MRI with T1 volumetric sequence performed within 1 year Exclusion Criteria: * Other cause of dementia * Participation in an AD therapeutic clinical trial * Protected adults (including individual under guardianship by court order),
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What it tests

  • Blood sample
  • Neuropsychological battery tests
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Where

1 site
Hôpital Cochin
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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