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โ† Trials
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Aging, Beta Blockers, and Thermoregulatory Responses

RecruitingPhase 4Ages 65 Years - anyAllUniversity of Texas Southwestern Medical Center
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In plain words

What the trial is, and whether it could suit you

This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Healthy and free of any significant medical problems * Normal resting electrocardiogram * 65+ years of age * Controlled cholesterol of less than 200 mg/dl * Controlled blood pressure of less than 140/90 mmHg Exclusion Criteria: * Known diseases or other chronic conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, uncontrolled hypertension, and uncontrolled hypercholesterolemia * Serious abnormalities detected on routine screening * Taking prescribed medications or over-the-counter medications that have known influences on either cardiac function or sweating * Current smokers, as well as individuals who regularly smoked within the past 3 years * body mass index โ‰ฅ31 kg/m2
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What it tests

  • Ambient Heat
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Where

1 site
IEEM Texas Health Presbyterian Hospital Dallas
Dallas, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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