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Enhancing Rehabilitation for Veterans With Serious Mental Illness

RecruitingNAAges 18 Years - 83 YearsAllVA Office of Research and Development
NCT06586164 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chronic functional disability, and impaired outcomes, causing a significant strain on support networks and the VA healthcare system. This study aims to introduce an innovative mental health therapy, Targeted Cognitive Training (TCT), to Veterans struggling with serious mental illnesses (SMI). TCT works to improve basic sensory information processing and, ultimately, clinical, cognitive, and psychosocial functioning. By using EEG biomarkers to identify Veterans with SMI receiving care within VA Psychosocial Rehabilitation and Recovery Centers who are most likely to benefit from this treatment, and b

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📋 Eligibility rules (as published)
Inclusion Criteria: * Veterans with SMI (e.g., schizophrenia, schizoaffective disorder, bipolar disorder, PTSD) being treated at PRRCs or co-located rehabilitative services. * Age 18 and 83 years. * Fluency in spoken and written English. * Ability to detect 1000 Hz tones binaurally at a 40-dB sound pressure level. * Ability to see with an acuity of 20/40 with both eyes tested together (corrected if applicable) by a standard printed Snellen eye chart reading card. Exclusion Criteria: * Estimated premorbid IQ below 70, as estimated via the WRAT-4 Reading subtest. * Active substance use other than cannabis within the last 30 days as determined by CPRS review, self- report, or positive urine drug screen (obtained as part of the screening process). * History of significant medical or neurological illness. * Inability to comprehend or provide informed consent.
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What it tests

  • Targeted Cognitive Training
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Where

1 site
VA San Diego Healthcare System, San Diego, CA
San Diego, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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