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VirtuAl Technology to Improve the Management of Perianal Crohn's (VAMP) - PROSPECTIVE

RecruitingNAAges 18 Years - 75 YearsAllNottingham University Hospitals NHS Trust
NCT06587646 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Crohn's is an inflammatory condition that can affect any part of the gut. Over half a million people in the UK live with Crohn's disease and about a quarter will develop a fistula near their back passage. A fistula is an abnormal connection between two surfaces of the body. These can be hard to treat causing pain and infection. Surgery is required to control infection and in extreme cases this can lead to incontinence or even formation of a stoma, when the bowel is brought to the skin and waste goes into a bag on the tummy wall. Patients with perianal Crohn's are usually referred to a surgeon by their medical team and subsequently undergo a MRI scan and an examination under anaesthesia (EUA) where abscesses (regions of fluid build-up) will be drained and a seton (plastic sling or suture) inserted through the fistula, or the fistula opened to the skin if this will not affect continence.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ability to give informed consent * Active perianal Crohn's disease as defined by clinical assessment with fistula or abscess formation * A clinical decision has been taken that surgery is required for perianal disease * Ages of 18-75 Exclusion Criteria: * Inability to consent * history of Proctectomy, * absence of a diagnosis of Crohn's disease, * perianal fistulising disease not secondary to Crohn's disease, * Rectovaginal fistulas * Malignant disease * Significant cardiovascular or respiratory disease * Neurological or cognitive impairment * Significant physical disability * Significant hepatic disease or renal failure * Subjects currently (or in the last three months) participating in another research project * Pregnancy or breastfeeding * If MRI is contraindicated (e.g. pacemaker). * under 18 years old or over 75 years old
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What it tests

  • Virtual Examination under Anaeastehtic - 3D reconstruction imaging
  • Standard Care - Written MRI report
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Where

1 site
Nottingham University Hospital NHS Trust
Nottingham, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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