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Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping

Recruitingn/aAges any - anyAllUniversity Hospital, Ghent
NCT06588543 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications. However, they still face challenges such as difficult catheter navigation and incomplete embolization. This study aims to improve the efficiency and safety of endovascular procedures by developing new preoperative planning methodologies. These methodologies involve mapping the cerebral vasculature and creating computational fluid dynamics (CFD) and artificial intelligence (AI) models to simulate blood flow. By using these models, interventional radiologists can better plan catheter navigation and predict embolization outcomes. This could lead to faster, more accurate procedures with reduced radiation exposure for patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects who are diagnosed with aneurysm or arteriovenous malformation * Subjects who are treated (or will be treated) with endovascular embolization and/or arteriovenous coiling * During and before/after the subject's intervention, medical images (MRI, 3D rotational angiography, DSA) were collected of the cerebral arterial vascular tree (which can be used to develop patient-specific models), including catheter location and use of contrast fluid to visualize the cerebral to make the arterial tree more visible. Exclusion Criteria: -Procedures during which no imaging was performed
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What it tests

  • Endovascular treatment
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Where

1 site
University Hospital Ghent
Ghent, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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