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← Trials
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Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment

RecruitingNAAges 50 Years - anyAllSharpTx
NCT06598163 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized controlled trial is to determine whether the digital health app Five Lives MED can improve cognitive function in people with mild cognitive impairment (MCI). The main question it aims to answer is: Can 12 weeks of using Five Lives MED improve global cognitive function in people diagnosed with MCI? Researchers will compare with a control group who receives a leaflet with standard health information. Participants in the intervention group will be asked to use the Five Lives MED app 3 times per week at home for 12 weeks. All participants, in both groups, will undergo cognitive testing and will complete questionnaires at baseline and exit.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of Mild Cognitive Impairment (also known as mild cognitive disorder \[ICD-10-CM; G31.84\] or mild neurocognitive disorder (DSM-5) * Age ≥ 50 * Participant or informant is willing and able to give informed consent for participation in the study * Ability to read and understand English (UK) or French (France) * Access to a mobile phone (Apple iOS 12.4 or above or Android 6.0 (Marshmallow) or above) or iPad (Apple iOS 12.4 or above only) with internet connection (mobile or WiFi). Exclusion Criteria: * Diagnosis of dementia or evidence of functional impairment inconsistent with MCI * Severe visual impairment * Currently undergoing any other cognitive remediation programme * Currently taking part in any other investigational study that in the opinion of the investigator may impact the data integrity of the current study * Physical impairment that makes using a mobile device impossible * Lack of access to an informant * Participant under guardianship * Unwilling or unable to tolerate or engage with study procedures * Physical impairment that makes standing/walking unassisted impossible.
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What it tests

  • Five Lives MED
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Where

7 sites
Hôpital Broca, Service de gériatrie Hôpitaux Universitaire Paris Centre, Université Paris Cité
Paris, France
Devon Partnership NHS Trust
Exeter, United Kingdom
Lancashire & South Cumbria NHS Foundation Trust
Preston, United Kingdom
Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom
Somerset NHS Foundation Trust
Taunton, United Kingdom
East London NHS Foundation Trust
London, United Kingdom
South London & Maudsley NHS Foundation Trust
London, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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