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PAS Balance Training for Parkinson Disease (PD)

RecruitingNAAges 20 Years - anyAllChang Gung University
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In plain words

What the trial is, and whether it could suit you

Gait initiation (GI) difficulty is a common problem in individuals with Parkinson's disease (PD), often linked to impaired anticipatory postural adjustments (APA). Currently, there are no targeted rehabilitation programs designed specifically for GI-related APA in PD patients. Research has shown that while motor learning deficits are common in PD, explicit learning is better preserved than implicit learning. Therefore, a GI-related APA training system using an explicit learning model could be particularly effective for this population. During motor learning, long-term potentiation (LTP) increases the excitability of the primary motor cortex. Paired associative stimulation (PAS) has been demonstrated to induce LTP-like changes in the motor cortex, making it a potential priming method to enhance motor learning. However, the priming effect of PAS targeted at leg muscles and the motor corte

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: \- Clinical diagnosis of Parkinson disease. Exclusion Criteria: * Musculoskeletal injuries on legs * Osteoporosis. * Any peripheral or central nervous system injury or disease patients.
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What it tests

  • Weight shift training and APA feedback
  • Paired associative stimulation
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Where

1 site
Chang Gung University
Taoyuan, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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