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Oncology, Undernutrition and Sensoriality: Links, Mechanisms and Levers for Action

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire Dijon
NCT06600295 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cancers of the upper aerodigestive tract account for around 4% of all malignant tumours worldwide. Colon and liver cancer are the most common digestive cancers. The epidemiology of liver cancer is changing, and the number of deaths from liver cancer has increased by 25% worldwide. In France, around 19,000 cancers of the upper aerodigestive tract and 88,000 new cases of digestive cancer are diagnosed each year (colon cancer remains the most common). Patients with these two types of cancer are at particularly high risk of undernutrition. In cancer patients, changes in diet may result from constraints linked to the cancer or possible after-effects, but also from personal choices (for example, adopting a healthier diet). Cancer and its treatment lead to changes such as increased nutritional requirements and hypercatabolism, or sensory changes (taste and smell), reducing pleasure and food in

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📋 Eligibility rules (as published)
Inclusion Criteria: Patient : * With newly diagnosed cancer of the oropharynx, oral cavity, colon or liver (at any stage). * For whom first-line treatment has been decided including radiotherapy, chemotherapy, immunotherapy and/or surgery. * Able to follow all study procedures in accordance with the protocol. * Have given their oral, free and informed consent to participate in the study. Exclusion Criteria: * Person not affiliated with national health insurance system * Person subject to a legal protection measure (curatorship, guardianship) * Pregnant women, women in labour or breastfeeding mothers * Adults who is unable to give consent * Minors * Person unable to read, speak, write and understand French * Patients with neuro-cognitive disorders (post-stroke, dyslexia, dyspraxia) or neuro-psychiatric disorders (dementia, autism) that make it impossible to assess taste sensoriality. * Patients with olfactory or gustatory disorders documented prior to the disease * Patient with another cancer currently being treated * Patients with a systemic disease or physical trauma affecting taste perception * Patients with kidney failure * Patients with sinonasal polyposis * Patients undergoing immunosuppressive treatment * Patients with an estimated life expectancy of less than 3 months
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What it tests

  • tests/questionnaires
  • biological samples
  • evaluation
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Where

1 site
Chu Dijon Bourgogne
Dijon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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