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โ† Trials
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Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 2

RecruitingNAAges 18 Years - 80 YearsAllUniversity of Wisconsin, Madison
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether brain stimulation technology can help people reach a meditative state quickly and easily without years of meditation training. The researchers want to see if this will help people distance themselves from their thoughts and feeling, and if this will lead to improvements in openness and wellbeing the same way meditation can. Participants will: * Complete questionnaires * Perform a guided meditation task (The Bell Task) * Wear a high density electrocochleography (hdEEG) cap * Undergo brain stimulation

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults, ages 18 to 80 of any identified gender * Medically healthy * English-speaking (able to provide consent and complete questionnaires) * Healthy adults who are meditation-naรฏve * Citizen or legal resident Exclusion Criteria: * Any current or past history of neurological disorders or acquired neurological disease (e.g. stroke, traumatic brain injury), including intracranial lesions * Any current or past history of bipolar disorder and/or hypomania * Any current or past history of psychosis * History of head trauma resulting in prolonged loss of consciousness; or a history of great than 3 grade I concussions * Current history of poorly controlled headaches including intractable or poorly controlled migraines * Any systemic illness or unstable medical condition that may cause a medical emergency in case of a provoked seizure (cardiac malformation, cardiac dysrhythmia, asthma, etc.) * History of fainting spells of unknown or undetermined etiology that might constitute seizures * History of seizures, diagnosis of epilepsy, history of abnormal (epileptiform) EEG, or family history of treatment resistant epilepsy with the exception of a single seizure of benign etiology (e.g. febrile seizures) in the judgment of a board-certified neurologist * Possible pregnancy. All female participants of child-bearing age are required to have a pregnancy test * Any metal in the brain, skull or head * Any contraindications to MRI * Any medical devices or implants (i.e. cardiac pacemaker, medication infusion pump, cochlear implant, vagal nerve stimulator, dental implants (this includes a permanent retainer)) unless otherwise approved by the responsible MD * Substance abuse or dependence within the past six months * Any medication that may alter seizure threshold i.e., ADHD stimulants (Adderall, amphetamine); Tricyclic/atypical antidepressants (Amitriptyline, Dioxepine, Imipramine Maprotiline, Nortriptyline, Bupropion); Antipsychotics (Chlorpromazine, Clozapine), Bronchodilators (theophylline, aminophylline); Antibiotics (fluoroquinolones, imipenem, penicillin, cephalosporins, metronidazole, isoniazid); Antiviral (Valacyclovir, Ritonavir); OTC (Diphenhydramine) * Claustrophobia (a fear of small or closed places) * Back problems that would prevent lying flat for up to two hours * Having experienced a traumatic event that caused lasting distress or required treatment * Motion sickness * Any hair braid, dreadlocks, hair pieces, or extensions which cannot be taken out or adjusted to permit comfortable and comprehensive participation before the MRI scans and/or stimulation sessions * Any head coverings or headdress that participant feels uncomfortable removing for the purposes of the MRI scans and/or stimulation session
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What it tests

  • Transcranial electrical stimulation (TES)
  • Transcranial electrical stimulation with temporal interference (TES-TI)
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Where

1 site
University of Wisconsin
Madison, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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