๐ฌIn plain words
What the trial is, and whether it could suit you
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
Sign in to get the eligibility rules as simple questions to take to your doctor.
๐ Eligibility rules (as published)
Inclusion criteria:
* English speaking
* Diagnosis of Long COVID
Exclusion criteria:
* Any history of:
* Coronary artery dissection or aortic dissection
* Neurological disease (e.g. dementia, Alzheimer's disease, or other brain-related disease)
* Cerebrovascular disease or stroke
* Aneurysm
* If currently has:
* Moderate-severe chronic obstructive pulmonary disease
* Uncontrolled moderate-severe asthma
* Moderate-severe bronchiectasis
* Moderate-severe interstitial lung disease, requiring the use of supplemental oxygen
* A necessity to use supplemental oxygen, for any reason
* New or worsening symptoms (decompensation) of heart failure
* Right heart disease due to chronic pulmonary disease/sleep apnea
* Uncontrolled myocardial ischemia or angina
* Uncontrolled heart arrhythmias
* Heart or lung infection (e.g. myocarditis or pericarditis)
* Left main coronary artery stenosis
* Moderate-severe aortic stenosis
* Pulmonary embolism, pulmonary infarction, or other blood clots
* Severe respiratory disease
* Chronic kidney disease
* Chronic liver disease
* Females of childbearing potential will complete a urine pregnancy test at their baseline visit to rule out pregnancy
* BMI \>40
* Study staff unable to obtain adequate signal for cerebral blood flow
๐
What it tests
- Acute Placebo Visit
- Acute Progressive Carbon Dioxide
- Acute Intermittent Hypoxia
- Training: Progressive Carbon Dioxide Ramping
- Training: Intermittent Hypoxic Exposure
Mayo Clinic in Arizona
Scottsdale, United States
๐ค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ always decide together with your own doctor.