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Prevent Cardiac Surgery Associated AKI Trial

RecruitingPhase 2Ages 18 Years - 70 YearsAllGeorge Washington University
NCT06620523 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected. Adverse events related to the study drugs will be collected.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult 18-70 years of age * Undergoing elective CPB (Cardiopulmonary Bypass) surgery * Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min Exclusion Criteria: * GFR (Glomerular Filtration Rate) \<45 ml/min * Solitary kidney * Status post-kidney transplant * Pregnant women * Allergy to CoQ10 * Allergy to Glutathione * Allergy to Cellulose
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What it tests

  • CoQ10 1200 mg orally with Glutathione 1000 mg orally
  • Group B: Placebo CoQ10 orally and Placebo Glutathione orally
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Where

1 site
George Washington University Hospital
Washington D.C., United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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