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Clonal Hematopoiesis of Indeterminate Potential in Heart Failure.

Recruitingn/aAges 18 Years - anyAllFROM- Fondazione per la Ricerca Ospedale di Berga…
NCT06626685 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is part of the Rico Macro-Project, a multidisciplinary research program promoted by FROM in collaboration with the ASST-PG23 and ATS Bergamo, aiming to investigate the role of clonal hematopoiesis on inflammation, studying in depth the mechanisms underlying the inflammatory process to determine their correlation with some important pathologies in different clinical fields (Hematology, Cardiology, Neurology, Pneumology, Gastroenterology, and Diabetology, etc.). In this context, the prospective observational study RICO-HF is developed. The RICO HF is the first project focused on CHIP and inflammation in the area of Cardiology, specifically in HF.

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📋 Eligibility rules (as published)
Inclusion Criteria: * consecutive patients admitted to the Cardiology Unit of the ASST Papa Giovanni XXIII Hospital, Bergamo for acute HF and patients attending the outpatient HF clinic of the same hospital for chronic HF * age \>18 years * written informed consent Exclusion Criteria: * chronic therapy with anti-inflammatories, steroids, immunomodulators, immunosuppressants, chemotherapeuthic agents * previous heart transplant * cardiogenic shock or cardiac arrest * recent acute coronary syndrome (\<3 months) * current acute infection requiring specific treatment * overt MPNs * primary myelodysplastic syndromes * malignant cancers * non-cardiovascular co-morbidity reducing life expectancy to \< 1 year * any factor precluding 1-year follow-up
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What it tests

  • Clinical and instrumental examination
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Where

2 sites
ATS BERGAMO Agenzia di Tutela della Salute
Bergamo, Italy
Asst Papa Giovanni Xxiii - Dip. Di Cardiologia
Bergamo, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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