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Screening Strategies Among High-risk Populations for Anal Cancer

RecruitingNAAges 30 Years - 80 YearsAllLisa Flowers
NCT06628570 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 30-80 years of age * Individuals with chronic impaired immune status * History of lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2 Exclusion Criteria: * Patients treated for aHSIL less than 6 months before screening * History of anal cancer and pregnant women.
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What it tests

  • HRA + Biopsy
  • Anal Cytology
  • Genotyping of anal hrHPV infection
  • CINtec®PLUS
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Where

4 sites
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, United States
University of Miami School of Medicine at Jackson Memorial Hospital (JMH)
Miami, United States
Grady Memorial Hospital
Atlanta, United States
The Ponce Center
Atlanta, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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