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Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)

RecruitingNAAges 7 Years - 10 YearsAllNational University of Singapore
NCT06631339 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control. The trial also aims to better understand the impact of light exposure on sleep and cognitive performance in children. This trial has 3 arms namely, (1) a technical intervention arm, (2) a digital intervention arm, and (3) a control arm. 1. technical intervention - which involves changing of classroom lighting in primary schools to ceiling lights that mimic the spectral composition of sunlight and fluctuates in intensity. Parents of children within that arm will have a sham smart-phone application (s-LightUP) 2. digital intervention - which involves standard classroom lighting and giving parents an interventional smart-phone application (i-LightUP) that will be coupled with their child's light and activity sensor

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subject must meet all the inclusion criteria below to participate in this study. 1. Written Informed Consent form from parent / legal guardian and assent from child subject has been obtained 2. Is between 7 to 10 years of age at start of study intervention which is 2 January 2025 or 1 January 2026 3. Studying in either Primary 2 or 3 classes of the participating school(s) in academic year 2025 or 2026. 4. Presenting visual acuity or best corrected visual acuity (BCVA) better or equal to LogMAR 0.2 (equivalent to Snellen 6/9 or better) in each eye 5. Normal Intraocular pressure (not more than 21mmHg) 6. No ocular conditions (e.g., optic nerve disease, glaucoma, retinal diseases) except for refractive error. 7. No ocular conditions affecting the accuracy of the ophthalmic examinations 8. In good general health with no significant systemic diseases that may affect eye health Exclusion Criteria: * All subjects meeting any of the exclusion criteria at baseline will be excluded from participation. 1. Previous or ongoing myopia control treatment (including but not limited to orthokeratology, atropine, pirenzepine, myopia control spectacle and contact lenses, light therapy) 2. Ongoing participation in other myopia prevention and control research trials 3. Any systemic or neurologic diseases (e.g. cancer, epilepsy, Kawasaki disease) known to affect eye health or make the participant vulnerable to the ophthalmic examinations (e.g., light flash) 4. Any other conditions precluding adherence to the protocol including unwillingness to refrain from myopia control treatment for the duration of the study
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What it tests

  • Light Intervention
  • Digital Intervention
  • Control Group
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Where

5 sites
National University of Singapore, Yong Loo Lin School of Medicine, Department of Ophthalmology, Eye N Brain Research Lab
Singapore, Singapore
Marymount Convent School
Singapore, Singapore
Bedok Green Primary School
Singapore, Singapore
Westwood Primary School
Singapore, Singapore
Wellington Primary School
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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