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Neurological Responses in Patients with Dentine Hypersensitivity

Recruitingn/aAges 18 Years - anyAllSheffield Teaching Hospitals NHS Foundation Trust
NCT06633627 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Dentine hypersensitivity (also known as sensitive teeth) is a common dental condition in which the dentine, a layer of sensitive hard tissue under the enamel of the teeth, becomes exposed making the teeth sensitive to stimuli, such as hot and cold. It poses a significant challenge for clinicians and affects patients' quality of life. The overall aim of the study is to understand if a way of measuring brain activity (electroencephalography \[EEG\]) shows a response to tooth stimulation, and see how these responses may be different in patients with dentine sensitivity. EEG records brain signals and can provide information about how the brain processes painful stimuli. EEG recording is a non-evasive and painless procedure. It involves using a cap with small sensors called electrodes to pick up brain signals. During the EEG assessment appointment, brain signals will be recorded throughout

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Adults 18 years and older; 2. Understands and is willing, able and likely to comply with all study procedures and restrictions; 3. Accepts the form of the study and signs a declaration of informed consent; 4. In good health (in the opinion of the clinical dental professional); 5. A minimum of 10 teeth not including teeth with crowns or bridges from upper right 4 to upper left 4 and lower right 4 to lower left 4; For patients with dentine sensitivity only (experimental group): self-reported sensitivity in at least 1 tooth; confirmed by response to air puff. Exclusion Criteria: 1. Adults currently using maxillary or mandibular orthodontic appliances; 2. Obvious signs of untreated caries, which in the opinion of the clinical dental professional, will affect the scientific validity of the study; 3. Periodontal pocket depth ≥4mm in the anterior upper or lower sextants; 4. Evidence of periodontitis. 5. Have a history of seizures; 6. Taking medications that affect brain responses; 7. Experience damaged skin on the scalp due to cuts, psoriasis, eczema, or other conditions; 8. Any participant who in the investigator's judgment will not comply with the study protocol; 9. Any participant who has difficulties in adequate understanding of English.
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What it tests

  • Recording of brain activity using electroencephalography (EEG)
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Where

1 site
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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