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โ† Trials
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Efficacy of Intramuscular Steroid Injection for Chronic Cough.

RecruitingEARLY Phase 1Ages 18 Years - anyAllMedical University of South Carolina
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In plain words

What the trial is, and whether it could suit you

The primary goal of this study is to test the hypothesis that injecting steroid intramuscularly is an effective treatment for unexplained chronic cough. This will be achieved through the design of a prospective, placebo-controlled, single-blind, randomized clinical trial in which one group of patients will undergo a steroid injection into the deltoid muscle and the second group will undergo a placebo injection into the deltoid muscle. Data to determine if a clinically significant difference exists between the outcomes of the two groups will be measured by a dichotomous yes/no response to improvement, the Leicester Cough Questionnaire, and a visual analogue scale for symptom severity. This will provide the answer to the general question of whether or not the intramuscular injections are clinically effective for patients with unexplained chronic cough. Furthermore, any adverse reactions wi

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * History consistent with chronic unexplained or refractory cough * Age โ‰ฅ 18 Exclusion Criteria: * Current smokers * Uncontrolled diabetes (A1c\>7%) * Patients on ACE inhibitors or Angiotensin II receptor blockers (ARBs) * Abnormal pulmonary function testing (PFTs) since start of the cough * Patients with uncontrolled obstructive sleep apnea * Abnormal chest X-ray within past 6 months * Uncontrolled reflux * Prior superior laryngeal nerve injection * Current neuromodulating medication use for chronic cough\*
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What it tests

  • Triamcinolone Acetonide Injectable Suspension
  • Saline injection
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Where

1 site
Medical University of South Carolina
Charleston, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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