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Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block

RecruitingPhase 4Ages 20 Years - 65 YearsAllFayoum University
NCT06636578 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In 2012 Blanco et al. \[1\] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries. PECS block includes PECS I and PECS II (modified PECS I) interfascial blocks. Since that time, PECS block has been used successfully with good results for a wide variety of surgeries on the chest wall such as radical mastectomies, breast-conserving surgeries, breast implant placement, automated implantable cardioverter-defibrillator (AICD)/pacemaker placement, intercostal drainage tube placement, and rib fractures. In this study, the investigators hypothesized that adding dexmedetomidine as an adjuvant to ropivacaine can result in the prolongation of the duration of anesthesia with improvement of the quality of postoperative analgesia of bilateral PECS block for patients undergoing cardiac surgery via midline sternotomy

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 20 - 65 years, * Ejection fraction (EF) \> 35%, * Elective isolated CABG, or Valve surgery Exclusion Criteria: * Poor left ventricular function with intra-aortic balloon pump support, * Recent myocardial infarction (last seven days), * Combined procedure (i.e., CABG + other heart/vascular procedure), * Emergency surgery, or Redo cases, * Hepatic or renal failure, creatinine \>1.5, * Patients with hemodynamic instability, preexisting infection at the site of block, allergy to local anesthetics, psychiatric illness, and patients with prolonged postoperative ventilatory course were excluded from the study.
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What it tests

  • dexmedetomidine
  • ropivacaine
  • fentanyl
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Where

2 sites
Fayoum University Hospital
Al Fayyum, Egypt
Mohamed Hamed
Al Fayyum, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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