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โ† Trials
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Viral Epidemiology of Bronchiolitis After Nirsevimab Implementation and Respiratory Evolution in Infants

Recruitingn/aAges 0 Months - 12 MonthsAllUniversity Hospital, Rouen
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In plain words

What the trial is, and whether it could suit you

Acute bronchiolitis in infants, mainly caused by the Respiratory Syncytial Virus (RSV), is a public health issue, in terms of morbidity and hospital costs. Nirsevimab, a long-acting antibody against RSV available for all infants under 12 months, could profoundly modify the epidemiology of the next epidemic seasons, with the increase of the frequency of the other respiratory viruses (endemic Coronaviruses, Metapneumovirus, etc) Monitoring viral ecology is important, as the impact of respiratory infections on morbidity in the short, medium and long term, but also in economic terms. Infants under the age 12 months with a first episode of bronchiolitis and consulting the emergency pediatric department will be included. A nasopharyngeal swab will be performed as routine care, and clinical data will be collected. Multiplex Polymerase Chain Reaction will be performed to identify respiratory

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Infant aged 12 months or less * Admitted to the pediatric emergencies services during one of the three epidemic years: 2024-2025, 2025-2026 and 2026-2027 * With clinical diagnosis of first episode of acute bronchiolitis by the emergency pediatrician * With nasopharyngeal swab for virological diagnosis Exclusion Criteria: * Refusal of one or more of the infants parents to participate in the study * Infants parents refused to be called back for follow-up * No nasopharyngeal swab taken
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What it tests

  • biobank
  • follow up
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Where

1 site
Rouen University Hospital
Rouen, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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