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Study of the Impact of Cataract Surgery on the Corneal Epithelium and Ocular Surface of Diabetic Patients

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Strasbourg, France
NCT06638424 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Diabetes is one of the most common fatal metabolic diseases in the world. Diabetes-induced ocular surface alterations are poorly understood. Indeed, it was once thought that the cornea, avascular, was immune to the effects of diabetes. A growing number of publications now demonstrate the opposite. These alterations affect up to 70% of diabetic patients at some point in the progression of their diabetes. Another common complication of diabetes is the early development of a cataract, requiring surgery. Diabetic patients are therefore more likely to require surgery at an early age than the general population. Diabetes and cataract surgery both induce corneal changes. Cataract surgery in diabetic patients is therefore at greater risk of corneal complications. Diabetes induces dysfunction of the main lacrimal gland, corneal neuropathy, meibomian dysfunction and a decrease in conjunctival mu

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patient (≥18 years); * Patient operated on for cataract at HUS between January 2022 and January 2024; * Patient who did not express his opposition to the reuse of his data for scientific research purposes; * Patient who benefited from the measurement of the above-mentioned judgment criteria during his pre- and post-operative consultations. Exclusion Criteria: * Presence in the medical file of the subject's opposition to the reuse of his data for scientific research purposes. * Prolonged use of stored eye drops; * Documented etiology of chronic alteration of the ocular surface (shingles, herpes, Gougerot-Sjogren syndrome, graft-versus-host disease); * Minor patient or under guardianship or curatorship.
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What it tests

  • Not listed
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Where

1 site
Service d'Ophtalmologie - CHU de Strasbourg - France
Strasbourg, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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