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The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis

RecruitingNAAges 18 Years - 40 YearsAllFuture University in Egypt
NCT06640231 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of endodontic obturation is to make a complete sealing along the length of the root canal system to ensuring the peri radicular tissue healing and sustained health. Disadvantages of gutta-percha-based root filling materials is lack of adhesiveness to canal wall dentin. So, a sealer or cement has to be used with gutta-percha to achieve a fluid-tight seal and fill the space between the canal wall dentin and the obturating material. Drawbacks of resin-based sealer are difficult preparation technique of deep root canal cavity which also limit dentin bonding, difficult to be removed from the canal in retreatment cases and its shrinkage during setting. Bio-ceramic root canal sealers become popular in recent years because of their unique chemical and physical properties. These sealers are consisting of biocompatible materials that resemble the of tooth structure natural composition so

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ranges from 18 to 40 years old. * No sex predilection. * Patients seeking root canal treatment. * Systematically healthy patient (ASA I, II). * Patient who can understand numerical rate scale and sign an informed consent. * Mandibular first molar teeth with: * Preoperative sharp (moderate or severe) pain. * Vital response of pulp tissue to cold pulp tester (ethyl chloride spray). * Normal periapical radiographic appearance. Exclusion Criteria: * Patients with American association of anesthesiologists (ASA) classification other than ASA T\& II. * Patients who have already ingested preoperative medication, such as analgesics, non-steroidal or steroidal anti-inflammatory drugs, within 12 hours of the start of treatment. * Patients with NSAIDs allergy. * Patients having two or more adjacent teeth needing root canal therapy. * Pregnant patients. * Patients with bleeding disorder. * Patients with long term corticosteroid use * Teeth having; * Necrotic pulp. * History or presence of swelling or fistulous tract. * Acute / chronic periapical abscess. * Mobility more than grade 1. * Pocket depth more than 5mm. * No possible restorability. * Previous root canal treatment. * Periapical radiolucency. * External or internal resorption. * Vertical root fracture. * TMJ problems, bruxism, clenching or traumatic occlusion. * Inability to understand and perform the given instructions.
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What it tests

  • sealer activation after cleaning and shaping with XP-Endo Finisher
  • negative control where canals are obturated directly without sealer activation
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Where

1 site
Future University in Egypt
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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