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This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.

RecruitingNAAges 6 Years - 14 YearsAllHacettepe University
NCT06641011 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on permanent molars affected by Molar-Incisor Hypomineralization in high caries-risk children. 2. To compare the effects of rinsing off the silver fluoride or not rinsing it off (blot-drying with cotton pellet) on sealant retention when the sealant is placed immediately after silver fluoride application, and 3. To measure the desensitizing effect of fissure sealant application following silver fluoride treatment on hypersensitive MIH molars.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients and their parents who consent to participate and have signed the informed consent form. * Patients with at least one permanent molar diagnosed with molar incisor hypomineralization based on EAPD guidelines. * Fully erupted teeth with ICDAS I or II lesions that necessitate the application of fissure sealants. * Teeth displaying demarcated opacities on the occlusal surface and at least one additional surface. Exclusion Criteria: * Teeth that have existing restorations or cavities. * Patients currently receiving orthodontic treatment. * Patients who are uncooperative during dental procedures. * Teeth affected by dental fluorosis or enamel defects associated with specific syndromes. * Children with systemic conditions requiring ongoing medication.
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What it tests

  • Immediate restoration (resin- based) after blot-drying silver fluoride application
  • Immediate restoration (GI- based) after blot-drying silver fluoride application
  • Immediate restoration (Resin based) after rinsing silver fluoride application
  • Immediate restoration (GIC) after rinsing silver fluoride application
  • Resin based fissure sealant restoration one week after silver fluoride (AgF) application
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Where

1 site
Hacettepe University Faculty of Dentistry, Department of Pediatric Dentistry
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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