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โ† Trials
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Effect of IL17 Inhibitor in Comparison With Anti-TNF in Patients With Ankylosing Spondylitis

Recruitingn/aAges 16 Years - 60 YearsAllSohag University
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In plain words

What the trial is, and whether it could suit you

Ankylosing spondylitis (AS) is a chronic, inflammatory autoimmune disease characterized by axial bone inflammation. The main clinical manifestations include back pain and progressive spinal rigidity, as well as inflammation of the hips, shoulders, and peripheral joints. Also, extra-articular manifestations, such as psoriasis, uveitis, and inflammatory bowel disease (IBD). Indicators of inflammation such as erythrocyte sedimentation rate (ESR) and Creactive protein (CRP), which are typically elevated in AS patients, particularly when peripheral joints are involved, these tests ultimately do not reflect the disease process and have limited sensitivity and specificity. Disease activity in AS has been measured by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), which includes only patient-reported measures. The assessment of Spondyloarthritis International society (ASAS) dev

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients fulfill the Assessment in Spondyloarthritis International Society (ASAS) classification criteria for Axial Spondyloarthritis. * Patients with disease duration more than 6 months. * Patients who failed conventional treatment and on bDMARDs (IL17 or Anti-TNF-ฮฑ). * Age above 16 years old. * Patient cooperative and can answer questions. * Patients who are able and willing to give written informed consent. Exclusion Criteria: * Other rheumatologic or collagen diseases. * Age below 16 years and above 60 years. * Uncooperative patients. * Patient not able and willing to give written informed consent. * Patient with other causes of platelet dysfunction, count irregularity.
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What it tests

  • CBC
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Where

1 site
Sohag university Hospital
Sohag, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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