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SSVC-CI During CABG

Recruitingn/aAges 18 Years - anyAllMilton S. Hershey Medical Center
NCT06645327 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To investigate the superior vena cava collapsibility index (SVC-CI), measured via transesophageal echocardiography (TEE), as a marker of fluid responsiveness. Two groups will be compared in this study. Groups will be identified by obtaining cardiac output (CO) by standard means using the TEE or pulmonary arterial catheter (PAC). Both of these monitors are considered standard for patient's undergoing coronary artery bypass grafting surgery (CABG) and recording initial CO readings. Based on CO, the patient's will be placed in study groups one or two. Participants with normal and mildly reduced left ventricular ejection fraction (LVEF \>40%) for group one and those with moderately to severely reduced LVEF (\<40%) in the second group. Following group separation, we will measure the SVC-CI and CO metric in both groups. The intervention will be an operating room table tilt test (head up

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 2. Participants with CAD undergoing CABG utilizing cardiopulmonary bypass 3. Participants who are able to consent for themselves 4. Primary language is English Exclusion Criteria: 1. Age less than 18 years of age 2. Participants with CAD undergoing off-pump coronary artery bypass (OP-CAB) 3. Severe cardiac valvular pathologies or active congestive heart failure 4. Participants in active arrhythmia such as atrial fibrillation and atrial flutter at the time of data collection. 5. Participants who are unable to consent for themselves 6. Primary language is something other than English
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What it tests

  • a change in operating room table position, which will mimic an IV fluid bolus
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Where

1 site
Penn State Hershey Medical Center
Hershey, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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