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Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke

RecruitingNAAges 18 Years - anyAllMassachusetts General Hospital
NCT06654414 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Smoking remains the leading preventable cause of death in the United States, and there are persistent and significant disparities in tobacco use among transgender and gender diverse (TGD) individuals. Stigma, discrimination, gender dysphoria, and other gender minority stressors likely contribute to these disparities, and the increased burden of gender minority stress may also be driving higher prevalence rates of anxiety and depression, both of which are more common among TGD individuals and among those who smoke relative to comparison samples. This study will (1) explore the ways in which gender minority stressors and associated anxiety and depression compromise smoking cessation among TGD individuals, identifying elements in an existing smoking cessation intervention that need to be adjusted to meet their unique needs; (2) adapt an existing smoking cessation intervention for TGD indivi

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. aged 18+ 2. self-reported difference between sex assigned at birth and gender identity 3. current use of combustible cigarettes (defined as self-reported 5 combustible cigarettes per day in any week in the past month and a carbon monoxide \[CO\] expired-air reading of ≥8ppm) OR current use of nicotine-containing e-cigarettes (defined by saliva cotinine level of ≥30ng/mL) with use of combustible cigarettes (5 cigarettes per day in any week in the past month) 4. desire to stop using tobacco products (defined by ≥5 on the Motivational Aspects of Smoking Cessation Questionnaire) 5. English-speaking. Exclusion Criteria: 1. unable to provide informed consent 2. current interfering untreated or unstable major health condition (e.g., bipolar, current psychosis) 3. current use of psychotherapy for smoking cessation 4. participation in Aim 1a procedures.
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What it tests

  • PRIDE QUIT
  • Enhanced Treatment As Usual (ETAU)
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Where

3 sites
Massachusetts General Hopsital
Boston, United States
Boston University - Charles River Campus
Boston, United States
Fenway Health
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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