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Family Members at INcreased-risk for Developing Inflammatory Bowel Disease

Recruitingn/aAges 14 Years - anyAllMassachusetts General Hospital
NCT06655415 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow unaffected first-degree relatives (who do not have IBD) over time to understand if their behaviors, diet, and biomarkers for IBD can help predict who gets IBD and if IBD can be prevented in these high-risk individuals. Participants will be asked once per year to complete a questionnaire and have their blood, stool, and urine collected. The anticipated length of the study (registry) is approximately 10 years or longer. Parts of this study, such as the questionnaires and stool and urine collection, may be done from home, while other parts, such as the blood draw, will need to be done from Massachusetts General Hospital.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ability to give informed consent * Ability to complete all study visits and study-related procedures * Ability to understand and complete study questionnaires * Must have at least one first-degree relative with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or IBD-unclassified) * Age ≥ 14 Exclusion Criteria: * Individuals with existing diagnoses of inflammatory bowel disease (ulcerative colitis, Crohn's disease, or IBD-unclassified) * Evidence of clinical signs or symptoms of IBD, which will be identified on pre-screening interview with the study coordinator.
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What it tests

  • Not listed
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Where

1 site
Massachusetts General Hospital
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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