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SISIPUSH: Evaluation of Hemolysis and Iatrogenic Anemia Using the Push-pull Method to Obtain Blood from Pediatric Patients with Central Venous Catheters

RecruitingNAAges 0 Years - 18 YearsAllUniversity Hospital, Ghent
NCT06657534 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Anemia is frequently observed during hospitalizations, both in adults and children. In addition to the fact that anemia can be caused by an acute or chronic condition, blood samples taken during the hospital stay contribute to additional blood loss (so-called iatrogenic anemia). For children, the relative amount of blood taken at each blood collection is greater than in adults. It is therefore expected that in children, due to the lower circulating blood volume, the relative impact of repeated blood sampling is greater and interventions such as sparing the number of blood samples or blood volume can have a relevant impact on the onset of anemia, the need for iron supplements or blood transfusions and the general clinical recovery. For children, only limited data are available on the development of iatrogenic anemia during hospital stay. In a study of children in an intensive care unit,

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📋 Eligibility rules (as published)
Inclusion Criteria: * hospitalized patient at the Specialist Pediatric Department of Ghent University Hospital * age 0-18 years * presence of a central venous catheter for diagnostic or therapeutic reasons of the type surgically placed (Hickman, port-a-cath) or non-surgically placed (vena jugularis interna, subclavia, femoralis,...) * patent catheter with possibility of infusion of fluids and collection of blood on at least one of the lumens * clinical and/or radiographic confirmation of correct central position of the catheter tip * at least one blood collection per week hospitalization expected or already planned Exclusion Criteria: * presence of a bloodstream or catheter related infection before or at the time of randomization
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What it tests

  • Push-pull technique
  • SOC (Standard of care)
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Where

1 site
Ghent University Hospital
Ghent, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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