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Amino Acid Loss During Continuous Renal Replacement Therapy

Recruitingn/aAges 18 Years - anyAllMedical University of Vienna
NCT06659835 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are: What amount of amino acids is lost over the duration of continuous renal replacement therapy? How do amino acid plasma concentrations change over time in patients with and without continuous renal replacement therapy? Amino acid concentrations will be measured in the effluent and in the plasma of patients receiving continuous renal replacement therapy as part of their regular medical care. In addition, plasma concentrations of amino acids will be studied in patients without renal replacement therapy.

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📋 Eligibility rules (as published)
Inclusion criteria: * Postoperative ICU patients * Age ≥ 18 years * Patients on enteral or/and parenteral nutrition given according to internal standard operating procedure A) CRRT group: \- CRRT treatment planned; all types of CRRT (continuous veno-venous hemodialysis (CVVHD), continuous veno-venous hemodiafiltration (CVVHDF), continuous veno-venous hemofiltration (CVVH)) B)Non-CRRT group: * no current or previous (\<30 days) continuous or intermittent RRT * no chronic kidney disease stage G3-G5 Exclusion criteria: * Preoperative intensive care patients * Patients with liver cirrhosis stage 1-3 according to the Child-Pugh classification * Patients with acute liver failure
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What it tests

  • Not listed
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Where

1 site
Medical University of Vienna
Vienna, Austria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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