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Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit

RecruitingNAAges 18 Years - 65 YearsAllHospices Civils de Lyon
NCT06660082 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The vestibulo-ocular reflex (VOR) induces a compensatory movement in the eye when the head is rotated, to maintain stable vision when we move. It originates in the peripheral vestibular system, which detects head movements. It is particularly effective for rapid head movements, as tested in the Head Impulse Test (HIT). In acute unilateral vestibular deficit (AUVD), the VOR deficit is compensated for by a substitution saccade, more commonly known as catch up saccade, that contribute to refocus the gaze and maintain vision during head rotations. Recent technological advances have made it possible to make high-quality recordings during HIT (video Head Impulse Test, vHIT), leading to the identification of substitution saccades of variable latency. Our team has shown that saccades of shorter latency lead to better visual function (Hermann et al., 2017) and that the cerebellum is involved in

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients with unilateral vestibular schwannoma and programmed surgery * vestibulo-ocular reflex gain : * on pathological side \> 0.50 * on healthy side \> 0.80 * all information's concerning the study given more than 15 days before surgery and consent collected the day before surgery Exclusion Criteria: * Radiotherapy treatment prior to surgery. * Resumption of surgery * Presence of bilateral vestibular schwannomas * Normal or Corrected to normal distance visual acuity \< 5/10 * Presence of other aetiologies that may explain the ataxic syndrome and/or oscillopsias * Oculomotor paralysis, ocular instability in primary position * Use of medications that compromise eye movement (psychotropic drugs) * Cervical spinal pathology with instability (contraindication for vHIT) * Cochlear implantation * Non-stabilized medical condition * Pregnant women. This exclusion criterion will be investigated by questioning the patient. * Patient under guardianship * Patient not affiliated to a social security scheme * Patient participating any other interventional study
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What it tests

  • Experimental treatment: Head movements
  • Sham treatment: only eye movements
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Where

1 site
Pierre Wertheimer Hospital - Neurological Hospital
Bron, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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