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The Effects of Exercise Intervention on Skeletal Muscle and Other Organs in Aged Population and the Discovery of Associated Circulating Biomarkers

RecruitingNAAges 65 Years - anyAllNational Yang Ming Chiao Tung University
NCT06660706 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This project aims to investigate the intricate interplay between skeletal muscle and adipose tissue during the aging process by integrating human studies. Utilizing interventional research and randomized trials combined with examining blood samples from elderly individuals engaged in exercise, we aim to investigate the effects of exercise on muscle health and explore the underlying mechanisms of muscle aging and related biomarkers. Interdisciplinary research allowed us to investigate the systemic impact of exercise on muscles. This approach allowed us to gain a better understanding of the interconnectedness of skeletal muscle and adipose tissue in the aging process and devise efficient strategies to reverse age-related changes. These findings hold promise for promoting a future society where long and healthy life is achievable for all.

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📋 Eligibility rules (as published)
Inclusion Criteria: * aged ≥ 65 years * slow gait speed (\<1 m/s in 6-meter walk test) or weakness (dominant handgrip strength \<28 kg in men, \<18 kg in women) Exclusion Criteria: * established diagnosis of dementia, Parkinsonism or other mobility-limiting, disable conditions * active, acute diseases receiving treatment, such as cancer, heart failure, COPD and so on * estimated life expectancy \<12 months * current nursing home residents
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What it tests

  • Multi-domain intervention
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Where

1 site
Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University
Taipei, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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