Evaluate the Efficacy and Safety of JMKX003002 in End-Stage Renal Disease Patients on Hemodialysis with Hyperphosphatemia

Inclusion Criteria: 1. Able to understand the procedures of this trial and provide written informed consent voluntarily; 2. Age ≥ 18 years, male or female; 3. On a stable hemodialysis regimen at a frequency of two or three times per week for at least 12 weeks prior to the screening visit; 4. Serum phosphorus within the trial-required range. Exclusion Criteria: 1. Any history of inflammatory bowel disease or diarrheal irritable bowel syndrome; 2. Pregnant or breastfeeding; 3. Any history of a parathyroid intervention; 4. Diarrhea or loose stools occurred within 1 week prior to randomization.