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Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)

Recruitingn/aAges 18 Years - 90 YearsAllClinica Universidad de Navarra, Universidad de Naโ€ฆ
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In plain words

What the trial is, and whether it could suit you

1\. Introduction Scheduled surgery requires patients to undergo a preoperative fasting period of at least 6 hours to reduce the risk of perioperative pulmonary aspiration. However, certain medications and conditions may delay gastric emptying, potentially increasing aspiration risk. These include diabetic gastroparesis and the use of glucagon-like peptide-1 (GLP-1) receptor agonists for the treatment of diabetes and obesity. GLP-1 receptor agonists are widely used due to their beneficial effects on glycemic control and weight reduction. However, one of their known effects is delayed gastric emptying, which may result in increased residual gastric content despite adherence to standard fasting guidelines. Recent reports have described cases of pulmonary aspiration during anesthesia in patients receiving GLP-1 receptor agonists, even after appropriate fasting. Given the increasing use of

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Adults patients ,ASA I-III, taking GLP-1 analog medications, undergoing scheduled surgery. Exclusion Criteria: 1. \- History of esophagogastric pathology or previous abdominal surgery. 2. \- Hiatal hernia/gastroesophageal reflux disease. 3. \- Autonomic nervous system disorders. 4. \- Neurological or neuromuscular diseases. 5. \- Use of medications/drugs that affect autonomic regulation and delay gastric emptying (opioids) or potentiate it (prokinetics). 6. \- Pregnancy. 7. \- Presence of arrhythmias.
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What it tests

  • Gastric Ultrasound
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Where

2 sites
Clinica Universidad Navarra
Madrid, Spain
CAUSA Salamanca
Salamanca, Spain
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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