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โ† Trials
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Fibroblast Growth Factor 23 and Risk of Cardiac Arrhythmias in Hemodialysis Patients

Recruitingn/aAges 18 Years - anyAllAntonio Bellasi
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In plain words

What the trial is, and whether it could suit you

Despite recent progress in the field of hemodialysis (HD), mortality remains unacceptably high, particularly due to cardiac arrhythmias. Recent evidence suggests that fibroblast growth factor 23 (FGF23) is implicated in the pathogenesis of cardiac arrhythmias and sudden death. However, several aspects of both the pathogenetic mechanism(s) as well as the actual association in individuals with Chronic Kidney Disease (CKD) and the effect of dialysis clearance of FGF23 need to be elucidated. The investigators aim at testing the independent association of FGF23 changes due to dialysis removal and electrocardiographic (ECG) abnormalities (namely QTc prolongation) in a well characterized sample of patients undergoing maintenance HD. The study will be developed in the Division of Nephrology, Ente Ospedaliero Cantonale.

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๐Ÿ“‹ Eligibility rules (as published)
The study envisages the enrolment of: * Adult subjects (\>18 years of age) who can sign an informed consent. * on maintenance HD (for at least 3 months) Exclusion Criteria: * history of cardiac arrhythmias at study recruitment define as atrial fibrillation or pace-maker assisted cardiac rhythm
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What it tests

  • Not listed
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Where

1 site
Servizio di Nefrologia, Ospedale Regionale di Lugano, Civico
Lugano, Switzerland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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