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Premedication on Post-endodontic Pain

RecruitingPhase 3Ages 20 Years - 50 YearsAllGulf Medical University
NCT06671743 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is: What is the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment after premedication. Researchers will compare \[alpha-chemo-trypsin, ibuprofen, and acetaminophen\] to see the intensity of post-endodontic pain.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Eligibility for root canal treatment Patients diagnosed with symptomatic irreversible pulpitis with normal apical tissue in mandibular molars Exclusion Criteria: * • Patient under any medication or analgesic intake for pain management. * Patients with any systemic health issues * Patient allergies to trypsin-chymotrypsin, ibuprofen, and paracetamol * Pregnancy. * Non-restorable teeth. * Immature roots. * Calcifications. * Resorptions.
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What it tests

  • Root canal treatment
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Where

1 site
Gulf Medical University
Ajman, United Arab Emirates
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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